Cord blood banking is a process of preserving the blood from the umbilical cord and placenta. It is done because the cord blood contains hematopoietic stem cells in a high quantity.
These cells are commonly known as stem cells and are used in the field of regenerative medicines. Additionally , they can also cure rare diseases like genetic blood disorders, immune deficiencies and even cancer.
However, cord blood processing is quite challenging as getting high-quality cord blood is crucial for maximum stem cell viability. So let's look at why stem cell viability matters and how maximum viability is ensured during cord blood processing.
Why Stem Cell Viability Matters?
Stem cell viability refers to the percentage of stem cells that are alive and can be used to treat a patient. The more viable stem cells we get, the more efficient it will be to treat the problem. It not only increases the chances of success of treatment but also allows storage for a longer period.
Moreover, sometimes, many procedures are dependent on stem cell viability and can only be done if the cord blood is of high quality. In such cases, stem cell viability must be optimal.
Factors Influencing The Viability of Stem Cells in Cord Blood
Immediate Clamping
At the time of delivery, clamping and cutting of the umbilical cord must be done immediately to prevent coagulation.
Sterile Collection
The blood should be collected in a sterile container with the anticoagulant present in it.
Temperature Control
The cord blood should be kept at a very consistent temperature of 4-8° C. If the temperature rises and drops frequently, then it can lead to stem cell damage.
Read also: How are Stem Cells Stored?
Centrifugation
It's an important step to separate the important components from the blood. It separates the stem cells and plasma from the blood which are important for transplantation.
Cryopreservation
Lastly, substances like DMSO must be used while preserving the cells at a cool temperature to prevent ice crystal formation.
Wrapping Up
To sum up, stem cell viability matters a lot during cord blood banking. These factors must be aligned perfectly to make sure to get the best stem cell viability in the cord blood. Here comes the role of Cryoviva Life Sciences, the best place to save your baby’s cord blood for a safe future of your family.
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